Would you like to participate in a clinical trial investigating psilocybin treatment for alcohol dependence?
The UBC B.R.A.I.N. lab is looking for participants for a clinical trial to evaluate the efficacy and safety of psilocybin-assisted psychotherapy in adults with Alcohol Use Disorder (AUD). The preliminary trial results concerning this therapy have been encouraging and no serious adverse effects have been observed.
The trial will enroll individuals with alcohol dependence. Current alcohol consumption should be heavy to qualify for the Study. The total duration of the trial will be approximately 29 weeks including 13 visits to the trial site and laboratory visits.
During the trial, the investigational product will be taken twice, one month apart (a total of two doses). Enrolled subject will receive either the investigational product or a placebo that does not contain the active drug. Once the investigational product has been administered, subjects will remain at the trial site for observation for approximately eight hours before returning home with their caregiver. In addition to receiving the investigational product, all subjects will participate in a motivational enhancement therapy program during the trial. Motivational interviews alone are known to have potential positive effects on reducing alcohol consumption.
You may be eligible for the trial if:
• You are over 19 years old
• You have alcohol dependence
• You use alcohol almost daily and in large amounts
• You wish to decrease the number of occasions on which you drink and/or the number of alcohol units you consume
• You do not use narcotics, Antabuse, naltrexone or mood-altering medications and you do not have hepatitis or liver or kidney failure or serious heart problems and you do not suffer from major depression
• It is possible for you to arrange a caregiver to accompany you for 24 hours after the drug administration
• You are not pregnant
The investigational product is free of charge. Reasonable travel expenses will be reimbursed and you will be compensated for your time.
If you are interested in participating, follow this link or QR code to see if you are eligible:
https://flex.redcap.ubc.ca/surveys/?s=M4ETYE9YPCKMKWDL
Or contact us directly at brainlab.clairvoyant@ubc.ca with any questions you have!
CREB Number: H22-01565 Page 2 of 1
CLA-PSY-201 Advertisement for Site 302, version 4.0 23NOV2022
Based on CLA-PSY-201 Advertisement for Canada, version 2.0, 03MAR2022
To learn more about the lab and this study, visit our website:
https://brainlab.med.ubc.ca/